ICAM1 antibody
Quick Overview for ICAM1 antibody (ABIN2469882)
Target
See all ICAM1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
-
-
Specificity
- Reacts with CD54 (ICAM-1), a 85-110 kDa type I transmembrane glycoprotein (receptor for rhinovirus). T
-
Purification
- Protein A Column
-
Immunogen
- ICAM1 monoclonal antibody was raised against Raji human Burkitt's lymphoma cell line (Human).
-
Isotype
- IgG2a
-
-
-
-
Application Notes
- ICAM1 antibody can be used in ELISA, and immunohistochemistry starting at 5 μg/mL.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- PBS, 15 mM sodium azide, approx., pH 7.4.
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handling Advice
- As with all antibodies avoid freeze/thaw cycles.
-
Storage
- 4 °C/-20 °C
-
Storage Comment
- ICAM1 antibody can be stored short term 4 °C. For long term storage aliquot and store at -20 °C.
-
-
- ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
-
Alternative Name
- ICAM1
-
Background
- He expression of CD54 is upregulated by activation, it is expressed on activated endothelial cells, T lymphocytes, B lymphocytes, monocytes, macrophages, granulocytes and dendritic cells. ICAM1 (CD54) is typically expressed on endothelial cells and cells of the immune system. ICAM1 binds to integrins of type CD11a / CD18, or CD11b / CD18. ICAM1 is also exploited by Rhinovirus as a receptor.
-
Gene ID
- 3383
-
UniProt
- P05362
-
Pathways
- Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling
Target
-